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Gwo-Jyh Chang


Gwo-Jyh Chang

TitleAssociate Professor                     

LabCardiovascular Electrophysiology and Pharmacology Research Lab


Graduated SchoolGraduate Institute of Pharmacology, College of Medicine, National Taiwan University, Taiwan

Ext.3481, 3497


Personal Web Sitehttps://www.researchgate.net/profile/Gwo-Jyh_Chang


Research Assistant: 2


Pharmacology; Cardiovascular Electrophysiology, Pathology and Pharmacology; Muscle Pharmacology, Ion Channel Pharmacology; Natural Product Pharmacology


  The strength of my research is the characterization of the pharmacological and electrophysiological properties of new drugs with antiarrhythmic, anti-heart failure or vasorelaxant effects. In the past few years, we also devoted in the studies of novel cardioprotective agents on the pathological remodeling of the heart in pressure overload, diabetic or myocardial infarcted animals.

  The well-established patch-clamp recording technique in our Lab is one of the most convincing pathways to evaluate the function of various ionic channels on dissociated cells. The application of this unique technique combined with various in vivo and in vitro cardiovascular research techniques can help us to explore not only the acute actions of new drugs with antiarrhythmic actions but also to reveal the electrophysiological remodeling processes during chronic cardiac diseases such as cardiac hypertrophy or failure. By close cooperation with investigators of other disciplines we shall explore many complicate questions about the pathological mechanisms and find potential therapeutic strategies of modern cardiac diseases.

Publications within 5 years