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Publications within 5 years

  1. Lian WS, Lo JY, Kuo CW, Chen YS, Hsieh CK, Wu SL, Ke HJ, Wang SY, Yu CP, Jahr H, Wang FS*. UTX compromises articular chondrocyte anabolism and aggravates osteoarthritis. Nat Comm 2020 (manuscript in submission).
  2. Wang FS, Chen YS, Ko JY, Kuo CW, Ke HJ, Wang SY, Kuo PC, Jahr H, Lian SW.  MicroRNA-29a delays osteoblast senescence and senile osteoporosis by targeting DNMT3b-induced FOXO3 methylation. Redox Biology 2020 (manuscript in submission)
  3. Lian WS, Kuo CW, Ko HY, Ke HJ, Chen YS, Wang SY, Kuo PC, Tai MH, Jahr H, Wang FS*. Irisin represses oxidative stress and mitigates osteoarthritis development through regulating mitochondrial function and autophagy. Antioxidant 2020;9:E810.
  4. Chen YS, Lian WS, Kuo CW, Ke HJ, Wang SY, Kuo PC, Jahr H, Wang FS.* Epigenetic regulation of skeletal tissue integrity and osteoporosis development. International Journal of Molecular Sciences 2020 21:E4923.
  5. Wang FS, Chen YS, Ko JY, Kuo CW, Ke HJ, Hsieh CK, Wang SY, Kuo PC, Jahr H, Lian WS. Bromodomain protein BRD4 accelerates glucocorticoid dysregulation of bone mass and marrow adiposis by modulating H3K9 and Foxp1. Cells; 2020;9:E1500.
  6. Lian WS, Ko JY, Chen YS, Ke HJ, Hiseh CK, Kuo CW, Wang SY, Huang BW, Tseng JG, Wang FS*. MicroRNA-29a represses osteoclast formation and protects against osteoporosis by regulating PCAF-mediated RANKL and CXCL12. Cell Death & Disease 2019;10:705
  7. Wu RW, Lian WSm Chen YS, Kuo CW, Ke HC, Hsieh CK, Wang SY, Ko JY, Wang FS*. MicroRNA-29a counteracts glucocorticoid induction of bone loss through repressing TNFSF13b modulation of osteoclastogenesis. International Journal of Molecular Sciences 2019;20:5141.
  8. Lian WS, Ko JY, Wu RW, Sun YC, Chen YS, Wu SL, Weng LH, Jahr H, Wang FS*. MicroRNA-128 repressed chondrocyte autophagy exacerbates knee osteoarthritis by disrupting Atg12. Cell Death & Disease 2018;9:919
  9. Lian WS, Ko JY, Chen YS, Ke HJ, Wu SL, Kuo CW, Wang FS*. Chaperonin 60 sustains osteoblast autophagy and counteracts glucocorticoid aggravation of osteoporosis by chaperoning RPTOR. Cell Death & Disease 2018;9:938.
  10. Hung PL, Hsu MH, Yu HR, Wu KLH, Wang FS*. Thyroxin protects white mater from hypoxic-ischemic insult in the immature Sprague-Dwaley rat brain by regulating periventricular white matter and cortex BDNF and CREB pathways. International Journal of Molecular Sciences 2018;19:E2573
  11. Wang FS, Wu RW, Lain WS, Tsai TC, Chen YS, Sun YC, Ke HJ, Li JC, Hwang JL, Ko JY. Sclerostin vaccination mitigates estrogen deficiency induction of bone mass loss and microstructure deterioration. Bone 2018;112:24-34.
  12. Huang YH, Yang YL, Huang FC, Tiao MM, Lin YC, Tsai MH, Wang FS*. MicroRNA-29a mitigation of endoplasmic reticulum and autophagy aberrance counteracts bile duct ligation-induced fibrosis pathogenesis in mice. Experimental Biology and Medicine 2018; 243:13-21
  13. Lian WS, Wu RW, Lee MS, Chen YS, Sun YC, Wu SL, Ko JY, Wang FS*. Subchondral mesenchymal stem cells from osteoarthritic knees display high osteogenic differentiation capacity through microRNA-29a regulation of HDAC4. Journal of Molecular Medicine 2017;95:1327-1340.
  14. Ko JY, Lee MS, Lian WS, Wen WT, Sun YC, Chen YS, Li WC, Wang FS*. MicroRNA-29a counteracts synovitis in knee osteoarthritis pathogenesis by targeting VEGF. Scientific Reports 2017;7:3584.
  15. Yang YL, Wang FS, Li SC, Tiao MM, Huang YH. MicroRNA-29a alleviates bile duct ligation exacerbation of hepatic fibrosis in mice through epigenetic control of methyltransferase. International Journal of Molecular Sciences 2017;18:192 (Equal first author)
  16. Wang FS, Lian WS, Weng WT, Chen YS, Sun YC, Wu SL, Ko JY. Histone Demethylase UTX counteracts glucocorticoid deregulation of osteogenesis by modulating histone-dependent and –independent pathways. Journal Molecule Medicine 2017;95:499-512